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Effect of delayed addition of IFN-γ on IL-11 production by cultured rheumatoid synovial fibroblasts (cultured RSF). Cultured RSF were activated with IL-1α (2 ng/ml), and then IFN-γ (200 U/ml) was added to the culture at the indicated time. Cultured supernatants were harvested for IL-11 measurement 24 h after stimulation with IL-1α. Each bar represents mean ± s.d. of four different wells.
