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. 1998 Nov;114(2):154–160. doi: 10.1046/j.1365-2249.1998.00717.x

Figure 2.

Figure 2

Blood pressure monitoring for passive systemic anaphylaxis. Twenty-four hours after the purified IgG fraction of anti-ovalbumin (OVA) serum injection, the mice were challenged intravenously with OVA. Blood pressure was monitored for more than 1 h after OVA injection. For the blocking of FcγR function, 2.4G2 MoAb (8 μg/g body weight) was administered intraperitoneally to CD40-deficient mice 90 min before passive immunization with the purified IgG fraction. (a) Wild-type mouse treated with the purified IgG of anti-OVA serum. (b) CD40-deficient mouse treated with the purified IgG of anti-OVA serum. (c) CD40-deficient mouse treated with PBS (control). (d) CD40-deficient mouse treated with 2.4G2 MoAb and the purified IgG of anti-OVA serum. Three independent experiments were performed with similar results. Representative data are shown.