Fig. 8.

Activation state of lymphocytes from NON mice after mycobacterial infection. Cell acquisition was performed gating each subset of lymphocytes (CD3⁺, CD4⁺, CD8⁺, IgM⁺, IgG⁺) and the percentage of CD69⁺ cells was determined. The number of CD69⁺ lymphocytes was derived from the percentage of CD69⁺ cells and the numbers of splenic CD3⁺, CD4⁺, CD8⁺, IgM⁺ and IgG⁺ lymphocytes. NON mice were intraperitoneally infected with 10⁸Mycobacterium avium bacilli or injected with the vehicle of the bacteria. M. avium infection induced a significant increase in the number of CD69-expressing IgG⁺ B cells, no significant differences being seen in either T cells or IgM⁺ B cells. 1,0E + 08 = 10⁸. n = 8. □, Control; ▪, M. avium.