Fig. 1.

Number of IFN-γ- and IL-4-secreting cells in 100 000 lymphocytes from peripheral blood, after stimulation with outer surface protein (osp) fraction (OF) from Borrelia afzelii in Borrelia-seropositive asymptomatic individuals (n = 17), patients with Borrelia infection (n = 25, some of these analysed at several times during the disease course, data from [15]) and seronegative controls (n = 10, data from [15]). All values are net values where the number of spontaneously IFN-γ- and IL-4-secreting cells, respectively, are subtracted. Negative values represent cases where antigen stimulation resulted in an inhibition of cytokine secretion.