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Expression of CD2 by CD8+ cells of naive animal 2 (percentages relate to numbers of CD8+CD2+ cells). Only 28% of CD8+ cells are recognized by anti-CD2 MoAb at day 9, and this lack of MoAb binding is maintained until day 11 (day of Butalex treatment, sample taken pre-Butalex). By day 13, when cytotoxic T lymphocyte (CTL) activity is at its peak, CD2 expression is completely restored.
