In vitro whole blood IFN-γ responses to prototype skin test antigen fractions, and purified protein derivative (PPD) and M. leprae sonicate, in different subject groups in Nepal (EC, endemic controls; CT, contacts; TT/BT, BL, LL, leprosy patients by classification). Each point represents mean IFN-γ measurement in day 6 culture supernatant for one subject; group median response is shown by a bar.