Fig. 3.

Cyclosporin A (CsA) significantly decreases B7.2⁺B7.1⁻ but not B7.2⁻B7.1⁺ B cells. Peripheral blood mononuclear cells (PBMC) from six normal donors were cultured for 48 h with or without 100 ng/ml toxic shock syndrome toxin-1 (TSST-1) in the presence or absence of 1 μg/ml CsA. Cells were analysed by flow cytometry for the expression of B7.2 and B7.1 on the same B cells. Results from each individual and geometric mean values are shown.