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IL-4 reduced CD4+ T cell and macrophage infiltration into the central nervous system (CNS). On day 14 p.i., the spinal cords from PBS- (□) and IL-4 (500 ng/rat) (▪)-treated rats were dissected. Numbers of infiltrating cells were detected by immunohistochemical staining. Data are representative of two independent experiments with similar results. *P < 0.05; **P < 0.01.
