Table 1.

Comparison of IL-4 and IFN-γ production by adult and cord blood CD4⁺ T cells*

*Resting CD4⁺CD45RA⁻, CD4⁺CD45RO₋ adult T cells and CD4⁺CD45RO⁻ cord blood T cells (5 × 10⁵/ml) were cultured with P815/CD80 cells (5 × 10⁵/ml). Anti-CD3 MoAb (UCHT1) was added at a concentration of 2 µg/ml. Anti-IL-4R MoAb (2.5 µg/ml) was added to the cultures for IL-4 production, and not to the cultures for IFN-γ production. Supernatants were collected after 72 h of culture and the IL-4 and IFN-γ concentrations in the supernatants were determined by ELISA.