Fig. 2.

Percentage of individuals demonstrating T cell proliferation (stimulation index (SI) > 3) in the presence of GAD65 peptide pools (1–9) among the 21 newly diagnosed insulin-dependent diabetes mellitus (IDDM) patients (▪) and 23 control subjects (□). For each peptide pool (1–9), the proportion of positive responses among the patients was compared with that among the controls. A significant difference between the response of peripheral blood mononuclear cells (PBMC) from patients and controls was only observed with peptide pool 7 and 9 (*P < 0.05, Fisher's exact test).