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Screening of thyroid-derived combinatorial immunoglobulin gene libraries with denatured (DN) or native (N)-thyroid peroxidase (TPO) yields Fab that, with one major exception, are encoded by similar VH and VL chain combinations. Fab grouping is based on the derived amino acid sequences of their D regions and the number of clones represented by each VH/VL combination is indicated in parentheses
