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Levels of VEGF secretion by unstimulated and stimulated (10 U/ml lipopolysaccharide (LPS)) peripheral blood mononuclear cells (PBMC) isolated from 21 rheumatoid arthritis (RA) patients (▪) and 21 healthy controls (□) after 24 h and 72 h in culture. Spontaneous secretion of VEGF by RA patients was significantly higher after 24 h and 72 h compared with controls. *P < 0.02 (unpaired t-test).
