Fig. 2.

Immunohistochemical detection of human cells in the inguinal lymph nodes (a,b,c; mag. × 100) and in the lungs (d,e,f; mag. × 200) of the Hu-PBL NOD-SCID mice. NOD-SCID mice were left untreated (a,d) or were pretreated with 1 mg TM-β1 (b,e) or with 1 mg TM-β1 and irradiation (c,f). Twenty-four hours later, 5 × 10⁶ Hu-PBL were injected intraperitoneally. Presence of human cells was evaluated 2 weeks after reconstitution. The human cells stain red following recognition of the human CD45 surface marker.