Table 1.
Quantification of αβ and γδ T cell subsets in the peripheral blood from patients with tuberculosis (TB) and leprosy, and healthy contacts
| CD3 | αβ | γδ | Vδ1 | Vδ2 | |
|---|---|---|---|---|---|
| TB (n = 5) | 66·5 ± 10·0 | 63·1 ± 6·8 | 3·1 ± 0·6 | 0·5 ± 0·3 | 2·8 ± 1·0 |
| (18·9 ± 2·8) | (17·9 ± 1·9) | (0·9 ± 0·2) | (0·1 ± 0·1) | (0·8 ± 0·2) | |
| PPD+ (n = 5) | 64·2 ± 9·3 | 55·8 ± 9·9 | 6·8 ± 2·2* | 1·4 ± 0·7 | 5·5 ± 2·2* |
| (13·5 ± 2·0) | (11·7 ± 2·1) | (1·4 ± 0·5)* | (0·3 ± 0·1) | (1·2 ± 0·5)* | |
| PPD− (n = 5) | 65·9 ± 11·2 | 62·9 ± 9·1 | 3·1 ± 1·1 | 0·9 ± 1·0 | 2·1 ± 0·6 |
| (13·2 ± 2·2) | (12·5 ± 1·8) | (0·6 ± 0·2) | (0·2 ± 0·2) | (0·4 ± 0·1) | |
| TT (n = 5) | 63·0 ± 9·0 | 56·9 ± 8·3 | 6·9 ± 2·0* | 1·1 ± 0·6 | 4·9 ± 1·7* |
| (16·9 ± 2·4) | (15·3 ± 2·2) | (1·9 ± 0·5)* | (0·3 ± 0·1) | (1·3 ± 0·5)* | |
| LL (n = 5) | 61·4 ± 7·1 | 57·1 ± 9·1 | 4·8 ± 2·0 | 2·6 ± 0·8 | 1·9 ± 0·9 |
| (14·0 ± 1·6) | (13·0 ± 2·0) | (1·1 ± 0·5) | (0·6 ± 0·2) | (0·4 ± 0·2) | |
| Lep(+) (n = 5) | 71·0 ± 13·8 | 64·2 ± 10·4 | 7·2 ± 3·1* | 0·8 ± 0·9 | 6·2 ± 2·6* |
| (14·2 ± 2·8) | (12·8 ± 2·1) | (1·4 ± 0·6)* | (0·2 ± 0·2) | (1·2 ± 0·5)* |
Fresh isolated peripheral blood mononuclear cells were labelled with specific MoAbs and analysed by flow cytometry as described in Materials and methods.
TT, Tuberculoid leprosy patients; LL, lepromatous leprosy patients; Lep(+), lepromin healthy contacts.
Data correspond to the arithmetic mean ± 1 s.d. of the percent of positive cells of five individuals in each group. Data between parentheses correspond to the arithmetic mean ± 1 s.d. of the number of cells/mm3 × 10−2.
*
P < 0·05 compared with PPD− healthy individuals.