Table 1.

Periodontal tissue destruction

	Ligatured side
	Bone loss			Control side
	X-ray	Histometry	Fibre loss	Fibre loss
SRL172, 0·1 mg	0·73 ± 0·095	0·78 ± 0·120	0·465 ± 0·082	0·042 ± 0·020
SRL172, 1·0 mg	0·70 ± 0·141	0·76 ± 0·137	0·472 ± 0·135	0·028 ± 0·039
Saline control	1·07 ± 0·122	0·99 ± 0·124	0·790 ± 0·171	0·105 ± 0·058
P values (t-test)
0·1s mg/control	< 0·001	0·002	< 0·001	0·006
1·0 mg/control	< 0·001	0·001	< 0·001	0·004