Table 1.

Modulation of oil-induced arthritis (OIA) by in vivo administration of an anti-CD8 monoclonal antibody

Treatment†	Incidence	Day of onset‡	Day of maximal arthritis score‡	Maximal arthritis score‡	Sum score‡
D10	12/14	14*	20**	6	46
OX8	13/14	11*	14**	6	67

^†1 mg anti-CD8 MoAb (clone OX8, n = 14) or isotype-matched control MoAb (clone D10, n = 14) was administered to DA rats 2 days before induction of OIA. Each group represents pooled data from two experiments.

^‡Median value of affected animals.

^*Significant difference between the two groups, P = 0·0005.

^**Significant difference between the two groups, P = 0·037.