Table 2.

Modulation of oil-induced arthritis (OIA) by in vivo administration of an anti-NKR-P1 monoclonal antibody, clone 10/78

Treatment†	Experiment	Incidence	Day of onset‡	Day of maximal arthritis score‡	Maximal arthritis score‡	Sum score‡	Log rank test§
D10	1	5/6	12	17	5	52	NS*
NKR-P1	1	6/7	14	18	6	41
D10	2	7/7	12	20	7	57	0·048
NKR-P1	2	5/7	14	18	6	61
D10	3	5/7	14	20	4	19	NS
NKR-P1	3	6/7	13	17	5	30

^†1 mg anti-NKR-P1 MoAb (clone 10/78) or isotype-matched control MoAb (clone D10) was administered to DA rats 2 days before induction of OIA.

^‡Median value of affected animals.

^§P value when testing the null hypothesis that there is no difference between the groups when taking the whole disease progress into account, using the survival analysis log-rank test.

^*Not significant.