Table 2.

Histological disease score

Grade 0 = Normal colonic mucosa

Grade 1 =Loss of one‐third of the crypts

Grade 2 = Loss of two‐thirds of the crypts

Grade 3 = The lamina propria is covered with a single layer of

epithelium and mild inflammatory cell infiltration is present

Grade 4 = Erosions and marked inflammatory cell infiltration are present

Randomly selected 15 fields (magnified 100 times) in each section were inspected and graded as below by a pathologist in our hospital who was blinded to the treatment protocol. By scoring the grades in 15 fields, the mean in each section was calculated.