Table 4.

Median serum IgG subclass and total IgE concentration in 13 gold-treated rheumatoid arthritis (RA) patients in a prospective analysis, range in parentheses

Time	IgG1, g/l	IgG2, g/l	IgG3, g/l	IgG4, g/l	IgE g/l
Start	9·0	3·4	0·56	0·41	23
	(5·6–19·6)	(1·4–5·5)	(0·24–2·0)	(0·1–2·19)	(1–1266)
End	6·7	2·5	0·52	0·32	15
	(4·6–15·6)	(0·87–5·2)	(0·23–1·3)	(0·13–1·56)	(1–1009)
P*	0·001	0·001	0·026	0·15	0·47

^*Paired Wilcoxon signed rank.