Fig. 3.

Antigen specificity (a–c) and genetic restriction (d–f) of lymph node T cell clones from B6 mice immunized in the foot pad with heat-killed Pseudomonas. Proliferative responses of individual clones in the presence of syngeneic, irradiated, splenic antigen-presenting cells (APC) (a–c) and allogeneic APC from B10.MBR mice (d–f). Clones were stimulated with heat-killed Pseudomonas (2·5 × 10⁷ colony-forming units (CFU)/ml) and mean ct/min values obtained in triplicate wells of control and antigen-stimulated cultures were plotted against each other. The results of one of three replicate experiments are shown; the s.d. never exceeded 25%.