Fig. 4.
Effects of captopril on activation-induced cell surface (a) Fas and (b) its ligand (FasL) expression on T cell hybridomas. N3-6-71 cells were cultured in control 24-well plates or in anti-CD3-coated 24-well plates (5 × 105 cells/well), in the presence or absence of 8 mm captopril. After 5 h, the cells were stained with anti-Fas antibody (a) or anti-FasL antibody (b), and then stained with a secondary FITC-conjugated goat anti-hamster antibody. Flow cytometric analysis was performed using a FACScan. These results are representative of a number of independent experiments.