Table 2.

Development of pathologically significant proteinuria in CD4^slpr^cg, CD4^mlpr^cg and CD4^s/mlpr^cg mice

		No. of mice with proteinuria/no. of mice examined
Age (months)	Sex	CD4slprcg	CD4mlprcg	CD4s/mlprcg
3	Male	0/10 (0)*	1/10 (0)
	Female	0/10 (0)	2/10 (20)
	Total	0/20 (0)	3/20 (15)
5	Male	1/11 (9)	2/11 (18)	2/11 (18)
	Female	0/11 (0)	5/11 (45)†	2/11 (18)
	Total	1/22 (5)	7/11 (32)†	4/22 (18)

^*Incidence of proteinuria in percent (≥ 300 mg/dl) is shown in parentheses.

^†Significant difference compared with CD4 ^s-lpr^cg mice: P < 0·05 by Fisher’s exact test.