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. 2000 Dec;122(3):350–357. doi: 10.1046/j.1365-2249.2000.01385.x

Fig. 2.

Fig. 2

Apoptosis of CD4+ T cells after antigenic and mitogenic stimulation. Three replicate cultures of peripheral blood mononuclear cells were incubated with medium, PPD, Mycobacterium tuberculosis (MTB) and pokeweed mitogen (PWM) from 24 HIV PPD+ controls (□), 30 HIV PTB+ patients (hatched), 14 HIV+ PTB subjects (cross-hatched) and 16 HIV+ PTB+ (▪) patients. Apoptosis was assessed using the TUNEL test in combination with anti-CD4–PE. Results are expressed as percentage of TUNEL (+) CD4 T cells. Indicated in the figure are the statistical significant differences (paired t-test), between the non-stimulated and the stimulated cultures within each subject group.