Table 1.
Clinical and routine laboratory data of the four subject groups
| Subject groups n = | HIV− PPD+ 25 | HIV− PTB+ 36 | HIV+ PTB− 26 | HIV+ PTB+ 28 |
|---|---|---|---|---|
| Clinical data | ||||
| Age (years) | ||||
| (mean, s.e.m.) | 29·8 (1·9) | 25·4 (0·8)* | 32·2 (1·4)†† | 29·5 (1·6)† |
| Sex ratio, M/F | 19/6 | 26/10 | 11/15*† | 11/17**†† |
| Body mass index (%) | 31·0 (0·5) | 30·6 (0·8) | ||
| Sputum FAB smear | ||||
| scarce/1+/2+/3 + | ||||
| (% of subjects) | 3 17 19 61 | 7 14 32 47 | ||
| Chest x-ray | ||||
| grade 1/2/3 | ||||
| (% of subjects) | 2·5 30·5 67 | 14 25 61 | ||
| Laboratory data | ||||
| Leucocyte count/μl | 5104 (259) | 9333 (711)** | 4969 (346)†† | 8014 (795)**‡‡ |
| Granulocytes | 2057 (154) | 4326 (356)** | 2040 (229)†† | 4057 (532)**‡‡ |
| Lymphocytes | 2244 (140) | 2253 (146) | 2100 (134) | 1911 (248) |
| Monocytes | 803 (68) | 2754 (323)** | 829 (168)†† | 2046 (214)**‡‡ |
| CD4 T cell count | 939 (56) | 888 (54) | 401 (60)** | 303 (49)**†† |
| CDC classification (% of subjects) 1, 2, 3 | 92 8 0 | 94 6 0 | 38·5 23 38·5** | 25 32 43**†† |
| CD8 T cell count | 524 (45) | 485 (43) | 1087 (85)**†† | 926 (162)*† |
| Viral load (log) | 4·9 (0·2) | 5·2 (0·1) | ||
Mean values ±s.e.m. in each subject group are represented. Differences between the subject groups were calculated using Student's t-test for independent samples:
*
P < 0·05
**
P < 0·01 versus HIV− PPD+ controls.
†
P < 0·05
††
P < 0·01 versus HIV− PTB+ patients.
‡
P < 0·05
‡‡
P < 0·01 versus HIV+ PTB− controls.
CD4 classes are according the CDC classification [40]: Class 1, CD4 ≥ 500/μl; Class 2, 200 ≥ CD4 < 500/μl; Class 3, CD4 < 200/μl.