Fig. 5.

Hydrogen peroxide production by the granulocytes from members of family B. For experimental conditions, see legend of Fig. 4. Left top, control cells (2% eosinophils) with and without phorbol myristate acetate (PMA); no eosinophil depletion was attempted. Left bottom, cells from mother II-2 (3% eosinophils), no eosinophil depletion. Right, cells from patient III-5 (26% eosinophils) before (top) and after (bottom) eosinophil depletion. The mother clearly shows one active and one inactive population of neutrophils.