Table 1.
Patient number | Glomerulonephritis class | Proteinuria (g/day) | SLEDAI score | Basal PAF (pg/106 cells) | IL-10-stimulated PAF (pg/106 cells) |
---|---|---|---|---|---|
1 | III | 2·9 | 14 | 500 | 750 |
2 | III + V | 3 | 15 | 450 | 780 |
3 | NB | 0·2 | 12 | 50 | 120 |
4 | IV | 2·4 | 4 | 35 | 45 |
5 | NB | 0·2 | 8 | 30 | 110 |
6 | V | 1·7 | 16 | 65 | 180 |
7 | IV | 0·5 | 4 | 85 | 90 |
8 | NB | 0·2 | 3 | 45 | 45 |
9 | III | 0·61 | 2 | 25 | 25 |
10 | III + V | 0·4 | 2 | 58 | 58 |
11 | NB | 0·18 | 4 | 48 | 65 |
12 | IV + V | 0·3 | 4 | 20 | 20 |
13 | III | 0·3 | 2 | 20 | 35 |
14 | III + V | 0·08 | 6 | 45 | 50 |
15 | NB | 0·3 | 4 | 50 | 110 |
16 | III + V | 0·3 | 2 | 88 | 86 |
17 | V | 2·3 | 6 | 35 | 44 |
18 | III | 1·4 | 4 | 28 | 42 |
19 | III | 2·1 | 22 | 56 | 120 |
20 | III | 1·7 | 4 | 46 | 45 |
21 | NB | 3 | 12 | ND | 225 |
22 | NB | 1 | 24 | 56 | 104 |
23 | V | 3 | 18 | 150 | 200 |
24 | III + V | 1·3 | 14 | 60 | 100 |
25 | V | 3 | 10 | 270 | 320 |
26 | III + V | 1·7 | 12 | 60 | 65 |
27 | IV | 7·3 | 22 | 90 | 365 |
Disease activity was indicated using the SLEDAI score. PAF production by monocytes was valuated in basal conditions and after IL‐10 (20 ng/ml) stimulation, as described in PATIENTS and METHODS. NB, Not biopsy.