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Lack of change in muscle or neuromuscular size as a result of postnatal AAVGalgt2 infection of myofibers at 2 weeks of age in mdx and wild type mice after 1 month of expression.
| Strain |
Myofiber Diameter (μm) |
NMJ Diameter (μm) |
||
|---|---|---|---|---|
| CT carbohydrate overexpression: | - | + | - | + |
| Wild type (gastroc) | 36±6 | 37±6 | 7±1 | 7±1 |
| Wild type (tibialis) | 25±2 | 22±2 | 7±1 | 7±2 |
| Mdx (gastroc) | 30±5 | 37±3 | ||
| Mdx (tibialis) | 25±6 | 35±4 | ||
P>0.05 in all cases
