Table 2.
Maximum striatum to cerebellum ratios and calculated distribution volume ratios (DVR relative to cerebellum) for VMAT2 radioligands in rhesus monkey brain. All studies done in the same monkey. DVR values obtained by Logan plot analysis.
STR/CBL | Striatal DVR | |
---|---|---|
(+)-[11C]DTBZ | 5.24 | 4.54 |
(±)-[18F]FE-DTBZ | 2.55 | 2.37 |
(±)-[18F]FP-DTBZ | 5.15 | 3.32 |
(+)-[18F]FP-DTBZ | 5.60 | 6.2 |