Table II.
Offspring | PE | L-NAME | Ach | Isop | Ca |
---|---|---|---|---|---|
NOS3FWT/−mat | 98.25±13.39 | 122.68±19.09 | −83.71±1.42‡ | −74.64±2.63 | 2.88±0.20 |
NOS3FKO/−pat | 92.13±11.42 | 138.85±24.39 | −95.17±1.95 | −94.25±4.46§ | 4.17±0.24§ |
NOS3FKO/+WT | 66.29±8.65† | 103.93±16.85 | −90.18±2.89 | −73.27±3.80 | 3.83±.047 |
NOS3FWT/−KO | 151.88±15.04* | 137.03±22.40 | 18.28±5.03* | 63.59±6.35 | 3.08±0.62 |
PE, Phenylephrine; Ach, Acetylcholine; Isop, Isoproteronol; Ca; Calcium
Maximal effect is expressed as the percentage of the reference contraction to 60 mM KCl or PE precontraction as appropriate.
P < 0.05 for NOS3FWT/−KO vs. all.
P < 0.05 is for NOS3FKO/+WT vs. all.
P < 0.05 is for NOS3FWT/−mat vs. all.
P < 0.05 is for NOS3FKO/−pat vs. all.