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. Author manuscript; available in PMC: 2008 Apr 1.
Published in final edited form as: Am J Obstet Gynecol. 2007 Apr;196(4):354.e1–354.e7. doi: 10.1016/j.ajog.2007.01.031

Table III.

Area under the acetylcholine concentration-relaxation curves (AUC; arbitrary units) and logarithm of the molar concentration that produces 50% relaxation (log IC50; a measure of sensitivity) in the carotid arteries of cross fostered female offspring (n = 4–10 mice in each group).

Offspring AUC Log IC50
NOS3FWT/−mat 229.65±5.78* 7.66±0.04*
NOS3FKO/−pat 286.73±11.80 8.07±0.09
NOS3FKO/+WT 262.81±13.57 7.91±0.13

AUC and IC50 were not calculated for the NOS3FWT/−KO because of the contractile response to acetylcholine.

*

P < 0.001 for NOS3FWT/−mat vs. NOS3 FWT/−pat.