Fig. 2.

Effect of annexin 1 (ANX-1; 100 μg/kg, i.v., hatched columns) or dexamethasone (DEX; 1 mg/kg s.c., cross-hatched columns) on the changes in leucocyte rolling velocity (a) and blood flow (b) induced by a lipopolysaccharide (LPS) superfusion (1 μg/ml, ▪) in mesenteric post-capillary venules as assessed by intravital microscopy. Time-matched controls (□) were superfused with normal bicarbonate buffer. The open arrow indicates the onset of the LPS superfusion, while the closed arrow indicates the time of the ANX-1 injection. Data are the mean and s.e.m. mean of n = 5–6 rats. *P < 0·05 versus controls; **P < 0·05 versus LPS-treated rats.