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Serial sections from the same granulation tissue from the patient with early onset periodontitis (EOP0, as for Fig. 1, showing the corresponding fields and demonstrating: in situ hybridization with specific digoxigenin-labelled oligonucleotide probes for the detection of: (A) IL-2 mRNA; (B) IFN-γ (C) no probe added (negative control); (D) IL-4 mRNA; (E) IL-6 mRNA; (F) IL-10 mRNA; mag. ×400.
