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HBsAg/Ab IC organ retention. Splenic and hepatic uptake and retention of HBsAg/Ab IC at 2 and 15 h in C1qa -/–(○) and C1qa+/+(•) mice. Horizontal bars denote means. (a) A highly significant reduction in the splenic uptake of IC in the C1q-deficient mice compared with the controls was observed at both 2 and 15 h postinjection (P < 0·0001 for both time-points). (b) No difference was found in the liver at these times.
