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. 2001 Mar;123(3):496–504. doi: 10.1046/j.1365-2249.2001.01475.x

Fig. 2.

Fig. 2

Induction of IgM-RF synthesis by PB B cells in the anti-CD3-driven system. Peripheral B lymphocytes (104/well) of healthy controls and patients with RA or other forms of arthritis (15: ankylosing spondylitis; 16: gout) were cocultured with T cells (clone K15; 105/well) in the presence of immobilized anti-CD3 mAb (50 μg/ml). Duplicate culture supernatants were harvested after 13 days and analyzed for IgM and IgM-RF concentrations. Data shown are the result of eight independent experiments.