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Presentation of HEL and HEL(46–61) peptide by DC to I-Ak restricted HEL-specific IC5·1 hybridomas. Increasing concentrations of the HEL(46–61) peptide (a, c) or intact HEL (b, d) were incubated with DC derived from CBA (a, b) or NOD.H2h4 (c, d), which had been stimulated for 18 h with (•) or without (○) LPS/IFN-γ. The production of IL-2 was determined using IL-2 dependent CTLL-2 cells. The result of one of two different experiments is shown.
