Table 1.
Characteristics of multiparous females and spouses
| Donor | Donor HLA typing | Spouse's HLA-typing | Last child's HLA-typing | Serum antibody specificity* | R† | Interval ‡ | Grav § |
|---|---|---|---|---|---|---|---|
| 1 | A3,A68(28),B51(5),B7 | A2,A29(19),B62(15),B35 | A2,A68(28),B51(5),B35 | A2 + B35 + B62 + B57 | 0·58 | 9 | 2 |
| 2 | A1,-,B7,B8 | unknown | unknown | A2 + A28 | 0·96 | 2 | 1 |
| 3 | A2,A24(9),B7 | A2,-,B51(5),B7 | A2,-,B7,B51(5) | B5 + B35 + B53 + B70 + B62 + B57 | 0·53 | 2 | 2 |
| 4 | A1,A3,B7,B8 | unknown | A2,A3,B7,B13 | A2 + A28 + B17 | 0·89 | 3 | 1 |
| 5 | A3,-,B51(5),B35 | A2,-,B7,B62(15) | A2,A3,B51(5),B62(15) | A2 + A28 + B62 + B17 | 0·86 | 7 | 2 |
| 6 | A3,-,B7,B35 | A1,-,B27,B35 | A1,A3,B7,B27 | A1 + B27 + B22 + B44 + B49 | 0·32 | 9 | unknown |
| 7 | A11,A29(19),B44(12),B56(22) | A2,-,B18,B60(40) | A2,A29,B44(12),B60(40) | A2 + A28 + B40 | 0·89 | 2 | 1 |
| 8 | A23(9),A11,B44(12),B55(22) | unknown | unknown | A2 + A28 | 0·85 | 3 | unknown |
| 9 | A3,A11,B14,B55(22) | unknown | A2,A11,B51(5),B55(22) | A2 + A28 + B5 + B35 + B53 + B49 | 0·63 | 2 | 1 |
| 10 | A1,A3,B7,B62(15) | A2,A3,B7,- | A1,A2,B7,B62(15) | A2 | 0·96 | 6 | 3 |
| 11 | A1,A25(10),B8,B18 | A2,-,B44(12),B60(40) | A1,A2,B8,B44(12)¶ | A2 + A28 + B12 + B40 + B17 | 0·88 | 14 | 3 |
| 11 | A1,A25(10),B8,B18 | A2,-,B44(12),B60(40) | A1,A2,B8,B44(12)¶ | A2 + A28 + B12 + B40 | 0·88 | 20 | 3 |
| 12 | A1,A32(19),B35,B38(16) | unknown | A1,2,B44(12),B35 | A2 + A28 | 0·92 | 5 | 2/3 |
| 13 | A1,A3,B8,B35 | A1,A2,B7,- | A2,A3,B7,B35 | A2 | 0·84 | 62 | 2 |
| 14 | A3,A34(10),B7,B62(15) | A2,-,B8,B60(40) | A2,A3,B7,B8 | A2 + B8 | 0·89 | 2 | 1 |
| 15 | A3,-,B7,- | unknown | A2,A3,B7,- | A2 | 0·56 | 2 | 2/3 |
*
antibodies in the serum of the same date of cell collection for BCPF expts, determined by CDC (except for donors 5:serum data 4 months after cell collection, and 10, 3 months after cell collection).
†
Coefficient of correlation (with Yates correction for small numbers).
‡
interval, in months elapsed between last pregnancy and PBL collection.
§
number of gravidities prior to PBL collection (2/3 denotes delivery of twins).
¶
typing of 2nd child given; 3rd child not available for HLA-typing.