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. 2001 May;124(2):180–189. doi: 10.1046/j.1365-2249.2001.01458.x

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© 2001 Blackwell Science Ltd

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Fig. 5 — Immunohistochemistry of human MCP (CD46) in representative cryosections of kidney, liver and brain from an hCD46Ge animal. Tissue sections (7 micron) were immunostained with a monoclonal mouse antihuman-MCP (CD46) Ab (TRA-2–10). In the kidney MCP (CD46) is expressed in the glomerulus and on the tubular epithelial cells (b). In the liver MCP (CD46) was detected on the hepatocytes and the bile duct epithelial cells (d); in the brain (cerebellum) on endothelial and glial cells (f). The corresponding kidney (a), liver (c) and brain (e) sections of a nontransgenic animal demonstrated no staining for MCP (CD46). Magnification × 100.