Table 2.
Effects of chemotherapy on percentage of B cell populations in BM
| Treatment | |||||
|---|---|---|---|---|---|
| Day | Control | CP | MTX | CyPh | |
| Pro/Pre | 12·9 ± 4·3 | ||||
| 2 | 0·4 ± 0·3* | 2·5 ± 1·2* | 0·2 ± 0·1* | ||
| 7 | 4·4 ± 1·8* | 11·3 ± 3·5 | 6·6 ± 1·0* | ||
| 15 | 13·2 ± 1·1 | 6 ± 3·3* | 6·9 ± 2·1* | ||
| 24 | 12·7 ± 1·3 | 6·9 ± 1·6 | 12·8 ± 3·8 | ||
| NF-B | 5·2 ± 2·1 | ||||
| 2 | 0·6 ± 0·4* | 1·5 ± 0·5* | 0·3 ± 0·2* | ||
| 7 | 0·7 ± 0·2* | 1 ± 0·2* | 0·1 ± 0·0* | ||
| 15 | 3·9 ± 0·5 | 1·8 ± 0·5* | 2·9 ± 0·6 | ||
| 24 | 4·2 ± 0·4 | 2·7 ± 0·8* | 3·9 ± 0·8 | ||
Effects were determined by three-colour flow-cytometry using IgM, CD90 and CD45R. Relative numbers (% ± standard deviation) of B cell populations were established by multiplying the frequency of the B cell subpopulation by the percentage of lymphocytes gated by FSC/SSC.
*
Indicates a significant difference with control values (P < 0·05).