Table 2.
Expression of mRNA for somatostatin receptor subtypes by human T-lymphocytes*
| Cell type | SSTR1 | SSTR2 | SSTR3 | SSTR4 | SSTR5 |
|---|---|---|---|---|---|
| P30 | – | + + + | + | + + | – |
| CCRF-CEM | – | + + + | + | + | – |
| Molt-4 | – | + + + | + | + + | + |
| Jurkat | – | + + + | + + + | + + | + |
| CCRF-HSB2 | – | + + + | + | + + | – |
| Peer | – | + + + | + + | + + | – |
| HUT-78 | – | + + + | + | + + | – |
| AF 24 | + + | + | + + | + + | + + + |
| CD2 | + | + | + + + | + | – |
| CD2(activated) | + | + | + | + | + + |
*
Relative expression of mRNA for somatostatin receptor subtypes in human leukaemic T-cell lines (P30, CCRF-CEM, Molt-4, Jurkat, CCRF-HSB2, Peer and HUT-78), the normal T-cell clone AF 24 and normal nonactivated and activated CD2+ blood T-cells was determined by RT-PCR and PCR (Figs 1–3). The findings from two identical experiments are summarized here: – no expression; + weak signal; ++ moderate to strong signal; ++ + strong signal.