Table 2.
Preoperative and postoperative IL-6 levels of the individual patients of the study groups, in vitro secretion of IL-6 (pg/ml) and TNF-α (pg/ml), and G/C polymorphism of the IL-6 gene at position −174
| IL-6 concentration (pg/ml) | ||||||
|---|---|---|---|---|---|---|
| Subject | Preoperative | Postoperative | IL-6 promoter region −174 Sfa NI | IL-6 concentration in vitro (pg/ml) | TNF-α concentration in vitro (pg/ml) | |
| Low | 1 | 1·79 | 398·85 | G/C | 2255·7 | 960·5 |
| 2 | 5·96 | 515·43 | C/C | 4462·7 | 948·5 | |
| 3 | 1·33 | 520·00 | C/C | 4305·3 | 1029·9 | |
| 4 | 1·61 | 432·04 | G/C | 2181·0 | 907·4 | |
| 5 | 1·72 | 42·59 | G/C | 3872·4 | 657·2 | |
| 6 | 0·77 | 479·74 | G/C | 3093·8 | 760·8 | |
| 7 | 3·56 | 294·09 | G/C | 4083·7 | 658·6 | |
| High | 1 | 4·92 | 958·57 | G/C | 4464·0 | 1796·5 |
| 2 | 4·08 | 720·48 | C/C | 3807·0 | 578·2 | |
| 3 | 2·08 | 734·56 | G/C | 3233·7 | 647·1 | |
| 4 | 4·80 | 1232·53 | G/C | 2761·6 | 422·5 | |
| 5 | 3·34 | 1343·57 | G/C | 2349·9 | 339·6 | |
| 6 | 3·05 | 787·86 | G/C | 4229·0 | 1318·3 | |
| 7 | 7·87 | 2202·52 | G/G | 3719·2 | 865·3 | |
| 8 | 0·89 | 632·00 | G/C | 2664·3 | 2500·8 | |
Low, patients with postoperative low secretion of IL-6; high, patients with postoperative high secretion of IL-6.