Table 3.

Serum TNF-α concentrations according to TNF-α −238 G/A, −308 G/A genotypes, BAT2 microsatellite and TNF-β intron polymorphism in 15 patients with cardiac surgery and CPB from study I

		TNF-α concentration (pg/ml)		RFLP marker of TNF‐α promoter region
	Subject	Preoperative	Postoperative	−238 BamHI	−308 NcoI	Microsatellite marker of HLA region BAT2	TNF-β intron NcoI
Low	1	1·00	3·40	G/G	G/G	140/150	1/2
	2	1·05	5·96	G/G	G/A	138/140	1/2
	3	1·30	2·89	G/G	G/G	140/146	1/2
	4	0·72	2·03	G/G	G/G	140/150	1/2
	5	1·00	2·49	G/G	G/G	140/150	1/2
	6	1·28	8·51	G/G	G/G	140/150	1/2
	7	1·05	14·99	G/G	G/G	142/142	1/2
High	1	1·40	8·39	G/G	G/G	140/150	1/2
	2	1·91	17·87	G/G	G/G	140/142	1/2
	3	1·40	17·66	G/G	G/A	138/138	1/2
	4	1·64	11·72	G/G	G/G	138/142	1/2
	5	1·40	17·60	G/G	G/A	140/152	1/2
	6	1·46	9·00	G/G	G/A	138/142	1/1
	7	1·50	9·32	G/G	G/A	140/140	1/1
	8	1·40	6·76	G/A	G/G	138/140	1/2

Low, patients with preoperative low secretion of TNF-α; high, patients with preoperative high secretion of TNF-α.