Table 3.

Data obtained in an in vivo neutralization assay to assess the neutralizing function of the fusion proteins

Group	No. of mice alive after Day 5	No. of mice alive after Day 14	Percentage survival
25 LD50, PV11 incubated with  dilutions of HRIG as shown
1/1000	10	10	100
1/5000	10	9	90
1/25000	9	1	11·1
1/125000	8	2	25
1/625000	10	1	10
25 LD50, PV11 incubated with  fusion proteins
IV-67-Fc	9	3	33·3
III-20-Fc	8	4	50
Virus Control (positive control and virus check)
25 LD50	10	0	0
2·5 LD50	10	5	50
0·25 LD50	10	7	70
Negative control (fusion proteins with diluent)
IV-67-Fc	10	10	100
III-20-Fc	9	8	88·8