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. 2001 Aug;125(2):274–282. doi: 10.1046/j.1365-2249.2001.01595.x

Fig. 6.

Fig. 6

Inhibitory and triggering CD94/NKG2 receptors inhibitors and triggering are functional on TAP-negative NK clones. (a) The TAP–NK clones GOR/28 (CD94/NKG2A−/C+) and GOR/50 (CD94/NKG2A+) and the TAP+ NKL cell line (CD94/NKG2A+) were analysed in redirected killing assay against P815 cells in the presence of anti-CD94 and anti-CD56 MoAbs. ▪, CD56; ▪, CD94. (b) Effector cells were evaluated in a cytotoxic assay against the HLA-deficient 721·221 cell line and HLA-E+ transfectant 221-AEH; experiments were carried out in the presence of anti-CD94, anti-HLA class I or anti-CD56 (control) MoAbs. ▪, CD56; ▪, CD94; □, HLA class I.