Table 3.
Summary of the correlation coefficients of %CD4+ and %CD8+T cells and log10 viral load (copies/ml) with the different CD4+ T cell subsets, expressed as %CD4+ T cells
| Correlation coefficients | ||||
|---|---|---|---|---|
| Phenotype | Values (min; max) mean ±s.e.m. | % CD4+ | % CD8+ | log10 VL |
| Memory/naive | ||||
| CD4+ CD45RO+ DR+ | 8·7 ± 1·80 (1·4; 51·3) | − 0·53** | − 0·29 | 0·27 |
| CD4+ CD45RO DR+ | 1·3 ± 0·25 (0·1; 7·3) | − 0·13 | 0·28 | 0·27 |
| CD4+ CD45RO+ DR | 32·8 ± 2·61 (13·2; 82·0) | − 0·37* | 0·25 | 0·04 |
| CD4+ CD45RO− DR | 57·2 ± 3·56 (6·1; 79·5) | 0·57** | − 0·36 | − 0·19 |
| CD4+ CD45RO+ CD38+ | 27·3 ± 2·27 (6·5; 74·2) | − 0·56** | 0·34* | 0·29 |
| CD4+ CD45RO+ | 41·6 ± 3·60 (15·9; 93·2) | − 0·56** | 0·34* | 0·17 |
| CD4+ CD45RA+ CD62L+ | 56·0 ± 3·39 (5·6; 83·7) | 0·71** | − 0·40* | − 0·26 |
| CD4+ CD45RACD62L+ | 31·0 ± 2·35 (12·4; 70·8) | − 0·48** | 0·08 | 0·36* |
| CD4+ CD45RA+ CD62L | 1·5 ± 0·42 (0·1; 11·8) | − 0·33* | 0·44** | 0·01 |
| CD4+ CD45RACD62L | 11·5 ± 1·84 (0·9; 49·9) | − 0·56** | 0·46** | 0·03 |
| CD4+ CD62L+ | 87·0 ± 2·11 (38·3; 97·4) | 0·54** | − 0·49** | 0·03 |
| CD4+ CD45RA+ | 57·5 ± 3·28 (5·8; 84·8) | 0·71** | − 0·36* | − 0·27 |
| Activated | ||||
| CD4+ DR+ CD38+ | 6·9 ± 1·46 (1·3; 52·4) | − 0·47** | 0·33 | 0·33 |
| CD4+ DR CD38+ | 75·3 ± 2·44 (35·7; 9) | 0·70** | − 0·42** | − 0·17 |
| CD4+ DR+ CD38 | 3·3 ± 0·59 (0·6; 15·9) | − 0·47** | 0·16 | 0·07 |
| CD4+ DR CD38 | 14·5 ± 1·35 (4·9; 36·3) | − 0·54** | 0·33 | − 0·14 |
| CD4+ HLA-DR+ | 10·0 ± 1·88 (1·9; 58·7) | − 0·52** | 0·31 | 0·29 |
| CD4+ CD38+ | 82·2 ± 1·74 (50·2; 94·0) | 0·58** | − 0·30 | 0·08 |
| RFI CD4+ HLA-DR+ | 15·6 ± 2·39 (3·8; 73·2) | − 0·45** | 0·16 | 0·31 |
| RFI CD4+ CD38+ | 49·5 ± 1·87 (26·4; 76·4) | 0·30 | − 0·51** | 0·19 |
RFI, relative fluorescence intensities. Level of significance
*
P < 0·05
**
P < 0·01. VL, viral load.