Table 1.

The effect of IC on MHC class II down-regulation is reversible

Treatment
agg-IgG	IFN-γ	% MFI of control
–	–	100
+	–	84
–	+	285
+	+	248

PBMC (1 × 10⁶ cells/ml) were incubated with medium or soluble agg-IgG (200 µg/ml) during 24 h at 37°C. Then, the cells were washed and incubated with medium or IFN-γ (240 U/ml) during additional 24 h as indicated. After this period, PBMC were stained with anti-HLA-DR and anti-CD14 antibodies. The table shows a representative experiment of n = 3. Data are expressed as percentage MFI of control cells and correspond to the CD14⁺ population of PBMC.