Table 1.
MET expression on cord and adult blood monocytes†
| Cultured with | |||||||
|---|---|---|---|---|---|---|---|
| Fresh | Medium | IFN-γ | IL-4 | IL-10 | GM-CSF | HGF | |
| Cord blood | 9·1 ± 3·3 | 2·5 ± 1·2 | 8·4 ± 2·2*b | 6·2 ± 1·8* | 9·5 ± 3·1* | 3·4 ± 1.5 | 1·2 ± 0·8* |
| Adult blood | 8·6 ± 2·1 | 2·9 ± 1·3 | 9·1 ± 2·5* | 2·1 ± 1·5 | 6·1 ± 2·2* | 4·1 ± 2.1 | 2·1 ± 0.6* |
†
MET expression of fresh and cultured monocytes was evaluated by flow cytometer. HGF down-regulated MET in both cord and adult blood. Other cytokines had various effects on MET expression. Results are expressed as RFI (MFI test antibody/MFI control antibody). Data are given as mean ± SD of three independent experiments.
b*
P < 0·05, compared with medium control.