Fig. 1.

Effect of dietary fatty acids on CD4 T-cell proliferation. Mice were fed diets enriched in SAF (black bars), EPA/DHA (grey bars) or FO (white bars) for 14 days. Splenic CD4 T lymphocytes were isolated and stimulated with various agonists as described in Materials and methods. Values (n = 5) represent the mean ± s.e.m. of net thymidine uptake (DPM). Different letters denote significant differences within each agonist group (P < 0·05). Abs, αCD3/αCD28 antibodies; 3/P, αCD3/PMA; P/I, PMA/Ionomycin.