Table 5.
Cytokine | HIV-1− term placentae (n = 15, pg/ml) | HIV-1+ term placentae (n = 15, pg/ml) |
---|---|---|
MIP-1α | 171 | 338 |
MIP-1β | 155 | 334 |
RANTES | 1249 | 1280 |
IL-1β | 129 | 169 |
IL-6 | 5046 | 14682 |
TNF-α | 41 | 49 |
IL-10 | 11 | 0 |
IFN-γ | 0 | 0 |
GM-CSF | 6 | 20 |
CSF-1 | 5845 | 4893 |
IL-8 | 23689 | 19437 |
Medians of secretion of cytokines and chemokines in supernatants of cultures of placental explants are expressed in pg/ml except for IFN-γ (IU/ml). Statistical tests were performed comparing early placentae with term HIV-1-negative placentae, or HIV-1-positive placentae with HIV-1-negative placentae.