Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Profiles of six CDR3 positions in HN clones (a) compared with the same positions in splenic sequences (b) of the same length. Amino acids are grouped according to their properties as A acidic (
), B basic (
), H hydrophobic (□), L polar (▪), G glycine 
, P proline 
, W tryptophan
and Y tyrosine 
. Positions 1, 2, 4 and 6 of the CDR3 profile of the HN clones shows clear restriction when compared with splenic sequences of the same length (P < 0·05).
