Fig.2.
PBMC from an MS patient (MS59) were cultured in the presence of MBP and a panel of peptides spanning the full length of MBP; proliferation was measured by 3H-thymidine uptake. The response observed at (a) the first time point was significantly different from that at (b) the second (after 8 months) and (c) third time points (3 months following the second sample). (▪) Day 5; (00077;) day 7; (□) day 10; (
00036;) day 12; (
00004;) day 14.